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Everything else that moves your blood sugar

Medications, alcohol, recreational drugs, illness, stress, hormones, heat and sleep: the interference on top of food, insulin and movement.

Food, insulin and movement are the daily levers. On top of them sits a long list of other things that push blood sugar up or down — often without anyone mentioning them. This page is an overview of that interference: medications, alcohol, recreational drugs, and the everyday things nobody lists.

Medications nobody warns you about

Beta blockers hide lows. They blunt the shaking and pounding heart that warn you of a low. Sweating usually survives, because it runs on a different nerve pathway — so an unexplained sweat is a low until proven otherwise.

Over the counter. Cough syrups carry real carbohydrate. "Non-drowsy" usually means a decongestant, which pushes glucose up. And supplements sold for "blood sugar support" can cause lows on top of your insulin.

Your pharmacist is free. They see every prescription from every doctor, including the walk-in clinic your usual doctor has never heard from. Use one pharmacy, say "type 1" every time, and carry the box to the counter.

None of this is a reason to refuse a medicine you need. People do stop needed medication after reading lists like this one — please don't. It is a reason to expect the change and plan for it. Much more in the Medications section.

Alcohol: the low arrives while you're asleep

Your liver has two jobs here: clear alcohol, and release glucose when you are running low. It will not do the second while it is busy with the first.

So the hypo doesn't come while you are drinking. It comes hours later, in bed. And drunk and hypo look identical from the outside. That is the whole danger — for the person, and for whoever decides to just let them sleep it off.

Sugary mixers push you up first, and the alcohol pulls you down later. Glucagon also works poorly after drinking — that one is an ambulance call. Alcohol is statistically the first substance most people meet, so it gets the same weight here as anything illegal.

Recreational drugs, without the lecture

This is harm reduction, not permission. The alternative to saying it is people doing all of it with none of the safeguards.

Nearly every drug interferes in the same three ways: you forget your insulin, your eating goes sideways, and you stop being able to tell a hypo from being high.

  • Nicotine — the slow one. It damages the same blood vessels diabetes already strains, and makes your insulin do less work per unit. Vapes are the same drug.
  • Cannabis — the forgetful one. Missed or doubled doses, uncounted munchies, and greening out looks exactly like a hypo — or like DKA. The only way to tell is to check.
  • Stimulants — speed, cocaine, MDMA. They burn carbohydrate while switching your appetite off, and the racing heart and sweating that warn you of a low are also just the drug.

NORS, 1-888-688-6677, will stay on the phone with anyone using alone, anywhere in Canada, at any age. Full detail in the Drugs and alcohol section.

And the things nobody lists

  • Illness and infection push glucose up sharply, even with no food. A cold can need more insulin, not less. See sick days.
  • Stress and adrenaline — an exam, a deadline, a fight, a job interview. Same mechanism as a sprint.
  • Hormones and cycles. Insulin sensitivity shifts across the menstrual cycle, through puberty and in pregnancy. Real, documented, and rarely mentioned.
  • Heat and cold. Warm skin absorbs insulin faster; cold slows it and can stop meters working altogether.
  • Sleep, shift work, travel. Changing when you sleep changes when insulin is needed. Time zones move the whole schedule.

That is the real answer to "why was today different?" There are more inputs than anyone can track, and an unexplained number is usually just an unexplained number. Most people are never told how many variables are genuinely in play — knowing it takes a lot of the self-blame out of a strange day.

Sources
  • Canadian sick-day medication guidance
  • National Overdose Response Service (NORS)

Last reviewed: September 24, 2026

Education, not medical advice. Every dose, ratio and target belongs with your own diabetes team.